Husband had first dose on june 18, so it has been about 10 and a half weeks since then. A few days ago he started having uncontrolled bms. Prior to this he was always constipated, so we were kind of shocked. His liver enzymes are also elevated. He does have some disease in the liver. He had a chest ct a couple weeks back due to fluid in the lungs and that also showed all the disease in his chest was stable, which was great news. it just seems like in the past week his health has deteriorated quickly... there are more bumps on his head and i even noticed a lump in his shoulder and side. is it even possible that this is all from the ipi working or should i prepare myself for sad news? his full body ct is tomorrow or tues and we get results the next day.