FDA Approves First Combination Therapy for Advanced Melanoma

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1/9/2014 10:47am
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Replies: 5

Good morning,

The FDA just approved the first-ever combination therapy for advanced melanoma! The combination involves a MEK inhibitor, trametinib, and a BRAF inhibitor, dabrafenib. Both drugs (developed by GSK) were approved by the FDA in May 2013 for use as single therapies. The MRF issued a statement on the approval, which you can read here.

Lauren - MRF

 

All good news.Just another weapon against the beast.Everyone out there fight as hard as you can for the day is soon we will victor over melanoma.It is all possible through the new targeted drugs approach.   aldakota22

 

 

So this would be only for people who have the BRAF mutation? 

MicheleM

Yes. BRAF mutated only.

This Combo is only for BRAF + patients.  Mek inhibitors are also being tested in conjunction with other drugs to see their effect, eg Gleevec and MEK, and other combinations.  Hurrry and get those studies done!

I'm me, not a statistic. Praying to not be one for years yet.

A good friend of mine has been on this combination since October.  Recent PET scans show no new tumors, and all of his other tumors except one have shrunk significantly.  He's having surgery this week to remove that stubborn one.  He looks great and feels good!  (Such a great thing to see after watching him go through biochemo!) 

Strength and Courage,

Susan