Any thoughts whether I should do Merck or MedImmune PD1 or something else?
Just found out today I failed the taf/mek combo. So I'm trying to figure out the next treatment. At least I have choices. I'm thinking either merck or medimmune PD1 but my gut tells me there is something better I just haven't found it but I do feel it is something with PD1.
Merck EAP PD1 will be the 3mg/kg which they only reported results for all doses not this low dose. Otherwise seems to be no washout period or anything else bad about it that I could find. I can get this at Mayo where I'm already in their system. If I do this it disqualifies me for MedImmune PD1. NCT02083484
MedImmune PD1 would probably be the 10mg/kg. Has a 28 day washout period. Is phase 1 so is fairly unknown. I can get this at Sarah Cannon where I'm already in their system. Can do this and still qualify for Merck PD1. NCT02013804
NCT01753089 wdvax shows up as PD1 on search which looks interesting but is phase 1.
NCT01621490 BMS PD1 the folks at MD Anderson were not too eager for me to be in this when I asked them. Not sure why since it does allow ipi failures.
Not really seeing any other PD1 out there that I qualify for that has started.
The failing of the taf/mek combo was fairly minor according to the doctor's PA. One tumor grew about 50%. 2 new supraclavicular lymph nodes demonstrating increased FDG uptake. Everything else either stayed the same size or shrank by a tiny amount.