So of the trials available, those two seem like the most promissing. I am currently stage III, but am preparing for the inevitable IV, which is when I'll be ellegible.
I'm thinking of first going with BRAF/MEK/PD-L1 combo because it seems like it's less drastic (TIL trial involves first nuking my entire immune system and being a bubbleboy for a month).
From lurking around the forum, it seems like BRAF/MEK combo is almost always a temporary bandaid, and the cancer tends to come back. Is this always the case? Is the combination with PD-L1 meds more likely to result in long-term remission, or should I go straight to TIL?
How effective is BRAF/MEK/PD-L1 and TIL at preventing brain mets? This is my worst fear. Given my line of work, even mild cognitive impairment could ruin me.
Anyone who's been through either is welcome to share their experience. How'd it turn out? What side effects did you get?