My husband has been on the control arm of the BRAF trial, and as we expected the DTIC did not work. We were obviously hopeful that he could have gotten the study drug and were willing to give the DTIC a shot, but I am now hoping that we didn't sacrifice precious time. He went into the trial with maybe half a dozen subcutaneous tumors and is leaving it with spots in his lung, liver and a golf ball sized tumor in his face and constant pain. Hopefully his participation helped further the FDA approval of the drug.
The next step is high dose IL2.