Good Day to you all from South Africa. My husband was diagnosed with Stage IV MM on 22 December 2010. The Melanoma has spread to 2 occipital lymphnodes, right cervical lymph node and additional smaller (sub-cm) nodes as well as a single node present in the posperior mediastinum and both lungs (muliple bilateral pulmonary metastases). He was given 3 options. No treatment, DTIC or the Clinical Trail. We went for a 2nd opinion and the diagnoses was the same. He was approved to take part in the OncoVex Clinical Trail. Luckily he got the OncoVex GM-SCF arm of the trail. He had his first injection on 18 January 2011 and the 2nd on 8 February 2011. His next injection will be 22 February 2011. He had side effects like headaches, vomiting, nausea, body aches and pains, tiredness and overall just not feeling well. With the 2nd injection he had with the mentions side effects diaree also. I have found only 1 guy in America that was on OncoVex for a year and he a "partial responder". Is there anybody out there that is willing to share their experience with OncoVex with us.