I'm currently in a trial with GSK using the braf drug GSK2118436. The mets in my lungs have all reduced in size and even disappeared in my liver and spleen. But a met in a porta caval lymph node doubled in size on my last scan and indicated "hot" on a followup PET scan. Apparently it is not responding to current treatment. i will have a followup appointment in a few days to discuss my options, but my understanding is that surgery may not be an option. Has anyone gone through radiation treatment on porta caval lymph nodes? Any other advice?