My husband was dx w/Stage IIIC 12/2010. I'm sitting here looking over the Pathology/Review Consultation Report received from Moffitt and it says: 3/3/06 Left mid back excision (4.8cm): malignant melanoma, Clark level III, 0.50mm in depth arising in association with the pre-existing melanocytic nevus, completly excised.
11/18/2010 Axillary mass, left needle biopsy: Metastatic poorly differentiated malignancy, consistent with metastatic melanoma.(see note) Note: Histological sections of the needle biopsy from the left axillary mass show tumoral cells with an epithelioid appearance, centrally placed hyperchromatic nuclei, indistinct nucleoli, and variable amounts of dusky cytoplasm. Immunohistochemical stains were performed, which showed tumoral cells to be positive for S-100, but negative for LCA, cytokeratin, and MART-1
12/1/2010 Lymph Node, Left Axillary, Dissection: Metastatic Melanoma in 2 of 16 lymph nodes (2/16), largest metastatic focus measures 3.3cm in greatest dimension involving greater than 90% of the lymph node area, subcapslar and intraparenchymal in location, extracapsular extension identified.
Three options given; 1. Follow with close observation. 2. clinical trial ipi vs. placebo. & 3. interferon.
My husband has polycystic kidney & liver disease and his insurance does not cover "Clinical Trial"
As of 12/30/2010 Pet/CT scan NED!!!
What do we do next.......