my husband has finished his yervoy treatment. he is now having lots of confusion, short term memory loss, behaviorial changes and cannot complete his sentences.
has anyone else had this problem?
I don't start Yervoy for a couple more weeks but i'd call the Dr right away...Prayers everything turns out ok..
I'm sorry to hear that. Have you notified your oncologist of those issues? Have you ever had a brain MRI? Or any brain mets treated before? I ended up having necrosis from radiation to the brain that affected my speech. I don't want to scare you but I'd notify your oncologist.
These are significant neurological symptoms. You should take your husband to the emergency room immediately.
My brother had brain tumors. Whenever they got to a certain size or when they started to bleed he had symptoms such as you describe. His oncologist told us to always take my brother to the ER when such symptoms happened because: 1) the ER at his hospital had their own MRI machine so patients didn't have to wait, 2) such symptoms could lead to a brain seizure so it's best to be in an ER for immediate treatment, and 3) it's much easier to get a patient admitted from the ER than by the oncologist trying to get him admitted.
My brother had 3 or 4 episodes such as you describe. He had one a few days after his first Yervoy infusion. His oncologist wondered if the Yervoy-activated immune cells were entering the brain and causing swelling around the tumors.
In any case, don't risk your husband having a brain seizure. Take him to the ER and then call your oncologist. Left untreated, brain seizures can cause death or permanent disabilty.
He has had several brain MRI's. They are all clear. We just got back from MDA. The doctors seem to think it may be some of the midication he is on. They have made some changes to his medication but I was just wondering if it could be a side effect of the Yervoy treatment.
Has your husband been taking any medications to deal with Yervoy side affects. Large doses of prednisone can affect behavior. He may have stopped taking any a while ago but for some the song may be gone but the melody lingers on. Both my husband and i have been on massive doses of prednisone for different reasons, His, asthma; mine, yervoy. Fortunately not at the same time. So we're still married to each other (and alive). .
Meet and talk to others about melanoma in our forums:
See also: History of the MPIP Forum
–CURE OM Forum
Or, visit the MRF Chat Room!
Questions to Ask Your Doctor
Email the MRF Nurse
Call the Patient Helpline
Get matched with a Phone Buddy
I'm newly diagnosed – what should I know?
Find other organizations that can help
Subscribe to get updates about melanoma & the MRF’s work in research, education & advocacy.
Helpline: (877) 673-6460
1411 K Street, NW Suite 800
Washington, DC 20005
(800) 673-1290 Office
(202) 347-9678 Fax
The Melanoma Research Foundation (MRF) is leading the melanoma community to transform melanoma from one of the deadliest cancers to one of the most treatable through research, education and advocacy.
The Melanoma Research Foundation is a 501(c)(3) non-profit organization.