MPIP: Melanoma Patients Information Page

The MPIP is the oldest and largest community of people affected by melanoma hosted through the Melanoma Research Foundation. It is designed to provide support and information to caregivers, patients, family and friends. Once you have been touched by melanoma—either as a patient or as a family member or friend of a patient—you become part of a community. It is not a community anyone joins willingly. But if you must be part of this group, you will find no better place to find the tools you need in your journey with this cancer, and the friends who can make that journey more bearable.

The information on the bulletin board is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.

Expand/ Collapse Topic
 
Replies By
View Topic
Kimmer's picture
Replies 4
Last reply 7/29/2010 - 11:27am
Replies by: kwahlbin, dian, Carver

Just testing the new format along with some other people.  For some reason I have to be Kimmer now instead of KimJ, but my other aliases have been Kim from Birmingham, Beaufort, Florida, Floridogz, etc.

Take good care, K.

And remember, no matter where you go, there you are. Confucius

Login or register to post replies.

tab22's picture
Replies 0

Just see whether I know how to use the new forum.

Login or register to post replies.

lhaley's picture
Replies 4
Last reply 7/29/2010 - 11:28am
Replies by: kwahlbin, dian, Carver

I'm just testing and discovered that I am now lhaley instead of Linda from Myrtle Beach.  That's ok because we are officially moving from the beach next Wed.!!  

This will take some time to get used to but it's interesting seeing how many times a post has been viewed and how many are online. If one person views a post twice does it go down as one view or two?

I just scanned downand saw that you can be alerted if people reply. That is a great addition!

Linda

Login or register to post replies.

Lori C's picture
Replies 6
Last reply 7/30/2010 - 4:49pm

Will is one week past his first carboplatin and taxol treatment.  He's also on a Fentanyl patch for pain, the first time his hip pain has been properly addressed.  So far, he's feeling very well - eating fine, (he wants to go out for Italian food for lunch) and actually seems slightly less fatigued than before he began chemo, which is a bit mysterious.   He goes back for round 2 on August 10th. 

At this point, we've been extremely pleased with the care from Dr. Howard Kaufman and the nurses at Rush in Chicago.  Dr. Kaufman, who is a surgeon as well as head of oncology and a melanoma specialist, is not exactly a touchy/feely kind of doc but he's honest, careful, attentive, and obviously a very excellent doctor.  A huge relief.  And the nurses have been wonderful, especially given Will has some special needs and is not always the easiest person to communicate with.

I'm hoping things will be stable for a while, at the very worst, and at best, this will really reduce the tumors.

Login or register to post replies.

Anonymous's picture
Replies 16
Last reply 7/19/2012 - 11:13am

Hi Everyone,

I visit MPIP , as well as, MIF to gain as much knowledge as I can on Mel. 

For what it is worth, I have noticed an increase in brain mets recurrences from people that post on the BB. Also, there seems to be a trend from people that have taken BRAF & Mef inhibitor drugs.

Maybe I am wrong, but if anyone has taken BRAF & MEK, it might be interesting to post whether or not you have a recurrence with brain mets & how long you have taken BRAF orMEK drug.

Just a thought..anyone have a opinion about Recurrences with  brain mets from BRAF/MEK Drugs?

Login or register to post replies.

Anonymous's picture
Replies 2
Last reply 7/29/2010 - 4:44pm
Replies by: gbaum, kwahlbin

 Help finding old posts in archives?

Login or register to post replies.

Anonymous's picture
Anonymous
Replies 3
Last reply 7/29/2010 - 4:02pm
Replies by: kwahlbin, Anonymous

Just wanting to see if the bold, italics, and underline features function and if inserting a link google.com shows and functions as a link directly in the body of the text. 

If all this works I'll give it a   and if not a  .  I see if you enter an emoticon and press the space bar it vanishes....so insert the emoticon, then left click your mouse  THEN press the space bar and presto.... yep, that works

Login or register to post replies.

Charlie S's picture
Replies 1
Last reply 7/29/2010 - 4:12pm
Replies by: kwahlbin

ONLY on registration are we asked for a birthdate, birthdate is not listed or asked for anywhere else, so why is my birthday (even though it is a fake birthdate) showing up in the right hand field when clicking on my profile?

I posted it here because many people do have privacy concerns, and this would certainly be a privacy concern.

Regards

Login or register to post replies.

Nancy's picture
Replies 2
Last reply 7/29/2010 - 8:10pm
Replies by: kwahlbin, sal d

I can't figure this one out- sorry -

You would think they would make it easier --

Thanks,\

Nancy

 

Login or register to post replies.

Jan in OC's picture
Replies 4
Last reply 8/6/2010 - 10:10pm
Replies by: Andyb, lilred75, Jan in OC, JenC

 We are planning to move soon and are considering Oregon.  Anyone from there that has a Melonoma oncologist?  Where do you get treatment if you live in Oregon? Husband (Dirk) is currently Stage IV in BRAF clinical trial at UCLA.

laughter is the best medicine

Login or register to post replies.

rlaraia's picture
Replies 4
Last reply 4/25/2012 - 11:24pm

I received Michelle's pathology report and the lesion that was removed last week was benign.  The report states it was a Junctional Melanocytic Nevus with nests of typical melanocytes.

Bo

Login or register to post replies.

Gowri Sivaraman's picture
Replies 3
Last reply 8/3/2010 - 1:55am
Replies by: JerryfromFauq, Carver, akls

My father's pet scan results came out clean and the oncologist asked us to follow up with blood tests after 4 months. He has been on interfereon after his lymph node removal last year. This forum has helped in educating me what are the different options available. We think about everyday as a gift these days and i am happy for this moment even though i don't know what the future holds for my father.

 

 

Login or register to post replies.

jim Breitfeller's picture
Replies 3
Last reply 7/2/2011 - 4:24am

One of many immunotolerance mechanisms that immune system has developed to distinguish between self and non-self antigens is regulatory T cells or Tregs.

These cells are recently characterized specialized T-cell subsets that actively suppress a variety of immune responses. Researchers have broadly classified Tregs into natural and adaptive Tregs. Natural Tregs are CD4+CD25+ T-cells that originate in the thymus and play a significant role in immune homeostasis and protection against autoimmunity. Adaptive Tregs are non-regulatory CD4+ T-cells that have up-regulated CD25 expression during pathological and inflammatory conditions such as cancers and infections.

Although the principal immunosuppressive mechanism of Tregs remains elusive, several in vivo experimental models have indicated that Tregs secrete large amounts of immunosuppressants including IL-9, IL-10 and TGF-Beta; upon activation.

 

These lymphokines are capable of inhibiting activation of Th1, Th2 cells and CTLs required for cell-mediated immunity, inflammation and antibody production. Certain recent experimental data and results even indicate that IL-2-IL-2R signaling is vital for development, maintenance, survival, expansion and suppressive activity of Tregs. Increased expression of certain other characteristic markers including CTLA-4, glucocorticoid-inducible tumor necrosis factor receptor (GITR) and OX40 has been identified on Tregs whose function inside these cells is still not clear. The TCRs displayed on Tregs are capable of recognizing and interacting with any peptide-MHC class II ligand having certain range of avidity. But, the contribution of TCR signaling and role of TCR-ligand interactions towards regulatory T-cell development needs to be determined.

 

Login or register to post replies.

Hi guys.

A huge thanks for the following advancement.

Activity is based upon the time of the last reply and not on the time of the original posting. This way an active discussion stays near the top of the board.

I used to find it annoying on the old board when I had to go back 3 or 4 pages sometimes to read new replies to an older active posting of interest to me.

I put that badly. All postings are important to me as they represent feelings of fellow patients but some postings capture my attention a teency more.

Good job guys

miket or talian44

Login or register to post replies.

 Hi,

   I think you are asking me why I didnt do systemic treatment....I was given that option along with the option of going to Boston for the ILP......and I went down for the consult at Mass General and felt the ILP was a good option for me....and I would "save" the bio chemo for "later"....so the ILO has an 85% "cure" rate.....according to the surgeon I saw who did the procedure...I was NED for 7 months after the procedure......so anyways after two more reoccurences (now have had 6), the only treatment offered (other than clinical trials, which werent offered but I looked into and decided I ddint want to do any yet), was radiation...so I thought I would do that again.....shut down the lymph channels as I have in transit (in the lymph system) mets.....does this help????

Donna in Vermont (now Vermont_Donna)........lol......stage 3 

Login or register to post replies.

Pages