The risk of recurrence increases with, the thickness of the primary tumor, with thicker tumors carrying greater risk than thin tumors, the presence of ulceration in the primary tumor and the presence of satellite metastases surrounding the primary tumor. The probability that melanoma will recur after appropriate treatment is characterized as low- intermediate-risk, or high-risk.
- Low-risk: less than 20% risk of recurrence
- Intermediate-risk: 20-50% risk of recurrence
- High-risk: greater than 50% risk of recurrence. High-risk melanoma has a high probability of having already spread to local or distant sites at the time of treatment.


