CURE OM Forum


Welcome to the CURE OM Forum, a community bulletin board designed to address the needs of the ocular melanoma community – patients and caregivers alike. Here you’ll find answers to questions about OM diagnosis and treatment, and support from people from all stages, levels of treatment and from all over the world.

Questions about what to post? Visit our forum posting policies for guidelines.

Expand/ Collapse Topic
 
Replies By
View Topic

I was diagnosed with ocular melanoma H 5mm, W.11.5mm and 12.12mm, on 7/2017, scheduled for plaque insertion 8/4 and 

6 days in hospital. I would like to hear from someone who has had this procedure so as to better 

understand the immediate post -op manifestations, such as vision, pain, comfortability etc.

Login or register to post replies.

hopeFlorida's picture
Replies 1
Last reply 7/6/2017 - 11:41am
Replies by: kaileetutt

I've been out of the loop for the past year while dealing with the mets to my liver and was wondering what the new latest greatest trials are out there?

I've completed 3 Opdivo + Yervoy treatments and about 6 months of Opdivo only. My tumors are stable now for about 18 months, but I am worried they will either continue to spread or start growing again. I cannot get them removed as they are small and scattered.

Any new news would be very helpful! THANK YOU!

Login or register to post replies.

betsyl's picture
Replies 1
Last reply 5/26/2017 - 10:55pm
Replies by: hopeFlorida

Hi all,

My husband's skin has started to itch now that the weather is getting warm. I've heard that moisturizer is good to use, but he doesn't like the greasy feel of lotions. Would it make sense to use antihistamines? Is the itchiness caused by a histamine response? He doesn't want to ask the doctor questions like this, doesn't want to be a bother..

Lately he's really feeling the fatigue. Plus he has some knee pain, which he's never had before. His mood is pretty down, which is understandable. Today he was morose. Maybe he should get counseling..I don't know.

He wants to go to his appointments by himself without me. Is that a common thing?  Maybe I'm getting on his nerves. (shrug)

The good news is he gets his fourth infusion tomorrow, which means he's almost half-way done with the 6-month course. The even better news is that the visible subcutaneous lump has melted away. 

He should be getting a scan soon. We'll find out tomorrow when. Keeping fingers crossed for good news.

We've been married for almost 17 years. I'm not willing to settle for less than 30. Ha ha.

-Betsy

 

 

 

Login or register to post replies.

Anonymous's picture
Anonymous
Replies 0

Hi All, I just want to ask if anyone ever tried using medical cannabis as an alternative meds? I have read many articles about medical marijuana and how it can help you in terms of chronic pain, glaucoma, eating disorder/anorexia, anxiety disorders and panic attacks, inflammation, even cancer and a lot more. Like this article about a marijuana strain hash plant. Cbd and thc are also new to me and I don't even smoke. If this is true I cant find any solid conclusive evidence that speaks to its efficacy. Any personal experience or testimonial would be highly appreciated. Thanks

Liang Chen

Login or register to post replies.

Anonymous's picture
Anonymous
Replies 0

Would anyone consider this an conjunctival tumor???? Waiting for results from the biopsy

https://goo.gl/photos/ohPqyXwSWivV9ofn7

Jenn

Login or register to post replies.

Anonymous's picture
Anonymous
Replies 0

Would anyone consider this an conjunctival tumor???? Waiting for results from the biopsy

https://goo.gl/photos/ohPqyXwSWivV9ofn7

Jenn

Login or register to post replies.

Anonymous's picture
Anonymous
Replies 1
Last reply 1/25/2017 - 7:10am
Replies by: SueGeorge

All-in-One CRISPR/Cas9 KO Kit is a highly effective and accurate gene editing kit which is based on the latest artificial endonuclease CRISPR/Cas9. All-in-One CRISPR/Cas9 KO Kit is applicable to modify genes in almost all kinds of mammalian cells.

Login or register to post replies.

Anonymous's picture
Anonymous
Replies 2
Last reply 1/25/2017 - 7:05am
Replies by: SueGeorge, TeoFriendly

Does anyone have this or know of someone.

Login or register to post replies.

Anonymous's picture
Replies 2
Last reply 1/25/2017 - 7:03am
Replies by: SueGeorge, DawnG

I am wondering if htere is anyone on this site that has had the immunotherapy comibnation of yervoy and opdivo for ocular melanoma.  I have read posts of skin melanoma with mets who had the treatment, but I am wondering about the eye since I willbe starting that immunotherapy combo soon.

Login or register to post replies.

Dear all,
I have the following question to community:
I have melanoma (Braf mutation) and now I have metastasis in spine L2.
Doctor has advised to make Stereotactic Body Radiation Therapy (SBRT) in L2
with the following dosage : 5 fractions with 4 Gray per fraction (20 total)
From my searching via internet it’s not enough in case of melanoma, I mean dose per fraction and total dose.
Did someone have that experience with radiotherapy in spine?
Pls advice

Login or register to post replies.

Recently diagnosed with melonoma. It has been removed however tumor was 4.7 mm mitosis was 7 not ulcerated and margin cleared by 0.3 mm. Seen oncologist and had fine needle as I have swollen node and shows cancer from pathology report. Nov 4th under going wide excision to clean up neck get more margin and SLN biospy removing all nodes on left side of neck where original melonoma detected. Well I am scared. My name is Lisa 3o have a family and now after this I have just stopped everything. Depressed anxiety you name it. My biggest fear is dying funny I work as a personal support worker.

They haven't given me a stage however I have been reading and if it's in nodes I am stage 3 I guess I'm confused some say two some say three from what I read. So far organs are OK no spread at this time.

Any advice would be greatly appreciated

Thank you

Lisa McCann

Login or register to post replies.

For many proteins and peptides, disulfide bridges are prerequisite for their proper biological function. Many commercialized proteins are cross-linked by disulfide bridges that increase their resistance to destructive effects of extreme environment used in industrial processes or protect protein-based therapeutics from rapid proteolytic degradation. Manufacturing of these products must take into account oxidative refolding—a formation of native disulfide bonds by specific pairs of cysteines located throughout a sequence of linear protein di-sulfide bond localization analysis.

Login or register to post replies.

Vrsomerset's picture
Replies 3
Last reply 9/6/2016 - 6:22am
Replies by: Anonymous, Vrsomerset, Adam-MRF

I was disgnosised with chorodial melanoma 2 weeks ago and had plaque therapy last week.  My regular eye doctor is excellent and has been keeping a close eye on the nevus for years.  It was removed this past Monday.  I'm being treated at the Wills Eye Hospital in Philadelphia.  I'm very scared that I may lose my eye and of the cancer spreading.  I had the biopsy done but don't have the results yet.  The tumor was small and they say the results of my treatment should be good.  There's not much information out there to read up on and I have no one to talk to about my fears and how they've made out.  Any help and info from other CM folks is appreciated.  Thank you, Vicki

 

Vicki spisso

Login or register to post replies.

srbf's picture
Replies 1
Last reply 8/27/2016 - 2:41am
Replies by: JoyJ

My mom is scheduled to begin (in 2 weeks) a clinical trial with Ipi (Yervoy)/Nivo (Opdivo) injections... from what i understand, it's pretty toxic and the side effects are quite severe.  Can anyone attest to this?  Are the side effects as severe as it seems?

Also, just wondering if anyone has tried Adoptive T-cell Therapy instead of Ipi/Nivo?  T-cell therapy seems less toxic and more specific to the individual, given that it uses the person's DNA.  Does it take too long to get this type of treatment set up?  (My mom is Stage IV metastatic ocular melanoma in her lungs).

Alternatively, are IL treatments equally as toxic as Ipi/Nivo?  are those treatments as effective?

Thanks,

Shelley

Login or register to post replies.

Nitric oxide (NO) is produced by three isoforms of nitric oxide synthase (NOS) and is a chemical messenger that reacts with free cysteine residues to form protein s-nitrosylation analysis (SNOs). S-nitrosylation is a critical PTM used by cells to stabilize proteins, regulate gene expression and provide NO donors, and the generation, localization, activation and catabolism of SNOs are tightly regulated.

Login or register to post replies.

Pages