My husband has been on Hoffman/Roche BRAF trial at UCLA since early Feb '10. After the first month, we started seeing red "bumps/splotches" that would appear on his arms or legs, they would swell up, be sore and itchy, then disappear a few days later. Doc said it was a rare side effect of the drug. No worries! But, since this weekend, those spots have gotten very large and developed blisters on them. Dirk was very uncomfortable. I emailed the Doc this morning and he said to stop the drug, has scheduled a CT scan and visit for Wed. Anyone else experience this??? Just a little worried cause he has had a bad week or two, really tired and in pain. He says all the "lumps" on and under his skin are hard and barking at him.
Jan (Dirk's wife)
WLE in Aug'09 arm and groin lymph nodes
Nov '09 new external mel on right torso
Dec '09 mets in liver, lungs, kidney, R shoulder bone