My husband was diagnosed with brain mets 3/12, had WBR, tolerated well, but tumors did not respond. He got 14 good months out of Zelboraf, tolerated well... then Zel quit 9/14. Gamma Knife in Aug 9/14, tumors responded. Has been on Dabrafenib/Trametinib combo since 11/14, recently added Yervoy to the mix & has had 2 infusions so far. A second Gamma in Feb and results today from all of the above.... brain mets shrinking and some necrosis from gamma! Most likely a third gamma in a few mos to get remaining tumors.
Keep that Positive Mind and Attitude!!
Stay Strong and prayers sure don't hurt either. :)