CAR T therapy

Posted By
Summer S.
2/10/2019 7:04am
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Replies: 6

Hello, 

Does anyone know of CAR T therapy? 

We have tried immunotherapy but with no luck, and we also tried targeted therapy but it is causing far too much toxicity. 

So, we are thinking of this new “clinical trial” therapy and I was wondering if anyone has experience/ information about it. 

Thanks,

S

ed williams - (2/10/2019 - 9:55am)

Hi Summer, here are a couple of links, first two are to Dr. Rosenberg at NIH explaining Til's and ACT based T-cell therapy. https://www.youtube.com/watch?v=_Xc7e7No4hQ

ed williams - (2/10/2019 - 9:56am)

This link is shorter version by Dr. Rosenberg of Til's research he has been doing at NIH in Maryland. https://www.youtube.com/watch?v=_Au5plbXm3Y

ed williams - (2/10/2019 - 10:04am)

One last good read about where the trials are being run and different type of T-cell based research. Best Wishes!!!Ed https://jitc.biomedcentral.com/articles/10.1186/s40425-018-0391-1

BrianP - (2/10/2019 - 8:26pm)

Summer,

I think CAR T is definitely worth looking into.  I felt very blessed to have the opportunity to do the trial I participated in.  I would look closely at TIL trials.  That would have been my first choice if I would have had a cooperating tumor to harvest T-cells from.  The trial I enrolled in did not require a tumor to harvest cells which is also nice for those who are surgery adverse.  

Unfortunately the trial currently says not recruiting but I know they are continuously opening and closing it based on patient load.  If you are interested in the trial message me and I can give you some points of contact and can tell you more about the trial.

https://clinicaltrials.gov/ct2/show/NCT02027935?term=autologous&cond=Mel...

Brian