Merck PD1 - a MIRACLE Drug!

Posted By
3/18/2012 3:18pm
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Replies: 23


I am posting my good news to share information on the Merck PD-1 trial.

I started this trial on 12/20/11. After only 3 infusions, I could see 2 subq's on my leg and chest start shrinking.

Last week, I had my first 12 week scans since starting to take this drug. My doctor told me that there was NO CANCER
anywhere in my body.

Starting the trial, I had tumors in my leg, on my chest and BOTH lungs. Being stage 4, this is truly a miracle after
only taking this drug for 12 weeks. My doctor told me, I am a “complete responder”.

I know of 2 other patients who started this trial in December 2011 with me. One patient with lung mets is a complete
responder. The other patient is a partial responder.

For those interested in this trial, here is the link:

I know that there are openings for this trial at UCLA Medical Center with Dr. Ribas. His email

Good Luck to Everyone fighting Mel.


audgator - (3/18/2012 - 3:33pm)

Although no one is happier than you, I guarantee there are a LOT of happy people reading this, including me. Congrats.


Gene_S - (3/18/2012 - 3:54pm)

Wow what wonderful news you received.  We are so happy for you.

NED is one thing my husband keep hoping for also.  He is making progress but is really hoping one day he can add to his profile. NED.

Sounds to me like it is time for you to celebrate.

Judy (loving wife and caregiver of Gene Stage IV)

Live 4 today. Thank God for all he has done for us. Looking forward to enjoying tomorrow.

MaryD - (3/18/2012 - 4:12pm)

Wow - that is fantastic news - so happy for you!    Thanks for sharing this as it will give hope to so many  . .and I wish you continued successful results!


Such good news, I may be taking part in that PD 1 trial at the UW Madison, will have my scans on the 26th and go from there. You bring so much hope to all of us.

Candi, Congrats!!!

Could you go though your time-line of therapies and doses with dates. I would like to see how it falls on a theoretical time scale. It is in my post called "Redirecting the Melanoma Tumor’s Microenvironment in Favor of the Activation of T-cells ". The second graphic.

Thanks in advance


Jimmy B

Candi13 - (3/18/2012 - 6:43pm)



2009-leukine, 2010-temador, and multiple surgeries



rbruce - (3/18/2012 - 6:04pm)

AWESOME News!!!!!!!!   I started this trial at UCSF on the 15th of this month and have been dreading having to wait 12 weeks to see if anything is working.  Having a really bad day today yand then I see your posting and turned my day around.  Thank you for sharing your wonderful news and I look forward to reading future posts about your continued great response.  Have you expereinced any side affects?  I had flu like symptoms, achey bones and muscles for a couple days after infusion but that seems to be gone.   Robert

The circumstances of our lives have as much power as we choose to give them. David McNally

Anonymous - (3/18/2012 - 6:47pm)

Hi Robert,


Do you know if there are any openings a UCSF?? How often do you get infusions???


Good Luck with this trial. I hope you are a complete responder.



rbruce - (3/18/2012 - 7:23pm)


No openings right now, but they are trying to get additional seats so I would contact them and get on the list.


The circumstances of our lives have as much power as we choose to give them. David McNally

Anonymous - (3/18/2012 - 7:40pm)

Thanks often do you have an infusion? how long is the infusion?  BettyJo

rbruce - (3/18/2012 - 7:57pm)

Infusion only lasts about 30 minutes.  Clinic vist with Dr., blood test before and after then EKG after takes a total of about 2-3 hours at clinic.     Robert

The circumstances of our lives have as much power as we choose to give them. David McNally

Anonymous - (3/18/2012 - 7:59pm)

how often are the infusions?

rbruce - (3/18/2012 - 8:06pm)

every 2 weeks.

The circumstances of our lives have as much power as we choose to give them. David McNally

Terrific, terrific,terrific! Thank you so much for sharing.  I'm raising a glass to your continued NED!!!


Become what you admire.

melmar - (3/19/2012 - 12:06am)

Congratulations!  Thanks for sharing the good news!

melmar - (3/19/2012 - 12:07am)

Congratulations!  Thanks for sharing the good news!

Eileen L - (3/19/2012 - 1:37pm)

Great news. Thx for posting. Gives all of us Stage 4 folks hope!

Eileen L

MeNDave - (3/21/2012 - 6:54am)

Congrats Candi!!  Doing a happy dance for you!  Thanks for posting the good news.... it gives many hope :)

Don't ever, EVER, give up!

Drew N - (3/23/2012 - 10:24am)

Even though I'm not actively fighting C these days, it's amazing to hear about the progress in the last year. Plus, my secretary's MiL just started 3475 yesterday, and we now have positive experiences to think about.

Drew Nelson

3b since 1/09

Linny - (3/23/2012 - 10:44am)

What wonderful news! I hope you went out and celebrated. smiley

Stage III, Unknown Primary; 1 positive node in left axilla

Candi13 - (3/27/2012 - 5:56pm)

Thank you all for the well wishes.

Update on results from Merck pd1 trial...I was told by my the study nurse today, that there were more patients having a partial response after their 12 weeks scans. Hopeful news for this drug!


caseym - (5/12/2013 - 10:31pm)

Hi everyone,

I just wanted to see how you are all going on the PD1 trial? My mum is 3rd on the list for the second round of trials in Australia. I want to give her the good news that i have already read about this drug and also any more details that you can provide to me.

I am so happy to hear that this trial seems to be working and so pleased to hear you are doing well Candi.

Look forward to hearing from you

melinda2 - (8/18/2014 - 10:47am)

THANK YOU for your post that just gave me a big, bright spot in my day.  My husband is Stage IV and will start the Merck PD-1 trial at Emory in two weeks.  He completed Yervoy recently and his cancer did not respond to it at all.  For southeast folks, I am aware that the PD-1 trials are being done at Mayo in Jacksonville as well as Emory in Atlanta.  Don't know if Moffet in Tampa has a trial program.