Hi Everyone. I have been lurking on this board for a few years now but now realize that by joining I will get the info. I need to help me decide on my next course of treatment. As you can see by my profile, I am a 57-year old woman with what my Oncologist calls 'low bulk' disease even though it is Stage IV. I would like to hear from anyone who has been through Interleuken 2 therapy. As a Canadian, I will have to travel to Pittsburgh for treatments. Right now, I do not know the hospital. Everyone has posted lots of information on side effects, etc. But how safe is it? I have the following choices: 1. wait and see with scans every 3 months. 2. Dacarbazine treatment here in Winnipeg. 3. Interleuken 2 treatment in Pittsburgh. Which has a better chance of success? Which treatment has the worst side effects? Does anyone know how quickly melanoma progresses from the lymph nodes to other areas of the body? That would help me with the 'wait and see' choice. I forgot to mention that for some reason, the one year of Interferon does not make me eligible for IPI trials. Only by trying and failing Dacarbazine or IL 2 will I be able to receive IPI. Who knows why? Anyway, I am thanking everyone in advance for responding to my questions.