Type 1 diabetes

Posted By
5/15/2018 2:22pm
Replies: 5

Has anyone else been diagnosed with Type 1 diabetes after starting Opdivo treatment?  I was after 3 treatments.  Boom there it was!  Good news is that I have been in remission since Mar 2017!

JuTMSY4 - (5/15/2018 - 4:31pm)

My doc expressed it as a concern and reason for stopping treatment depending on how long I was NED.  

Lucas - (5/15/2018 - 5:25pm)

I developed type 1 diabetes after 5 infusions of keytruda. This was during the stage 3 adjuvant trial. I stopped treatment at that point because of the severity as well as an elevated liver. Also my doctor thought it was a great response. I had a local recurrence 7 months later and am still dealing with that. However I have been clear of anything distant for 18 months. I’m probably the only other person on this forum with that side effect because it’s so rare.

Raeofsonshine - (5/17/2018 - 2:47pm)

I was diagnosed with T1D after 2 combo treatments.  Lost my thyroid and had elevated liver counts that after steroids was reversed.  My doc told me that T1D was unlikely to happen but then had 3 patients in a row have it happen.  So it goes, the treatment is just as unpredictable as the disese itself (Mel that is).  Best of luck!

buffcody - (5/20/2018 - 10:38am)

I'm one more of the T1Diabetes crowd.  It was diagnosed after 5 sessions of nivolumab, the first of the 5 being one that included ipi as well.  I'm almost 2 years into it as a part of my life.  I showed up NED just about a year ago and have stayed that way since.  I sure don't enjoy having to measure my sugar 4 times a day minimum and shooting up with insulin at least that many times daily, but NED beats the inconvenience and the aggravation.  I was only the second person at the University of Michigan Health Center to be diagnosed as a result of nivo as a type 1 diabetic.  Not sure what the number is today.

Bubbles - (5/20/2018 - 9:39pm)

Hey Frank! Good to see you around these parts!!  Sorry for the diabetes.  But, super glad to hear you are still NED!  That's great!!!  celeste