MPIP: Melanoma Patients Information Page

The MPIP is the oldest and largest community of people affected by melanoma hosted through the Melanoma Research Foundation. It is designed to provide support and information to caregivers, patients, family and friends. Once you have been touched by melanoma—either as a patient or as a family member or friend of a patient—you become part of a community. It is not a community anyone joins willingly. But if you must be part of this group, you will find no better place to find the tools you need in your journey with this cancer, and the friends who can make that journey more bearable.

The information on the bulletin board is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.

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Anonymous's picture
Replies 7
Last reply 8/1/2010 - 5:47pm

The last two mornings I have been extremely dizzy. Once in the shower. Had to close my eyes and hold onto the shower door. Couldn't even open my eyes or move to sit down on the bench in the shower. This morning, my husband had to help me walk down the hall. I could not walk without his assistance, and even struggled with his help. But once I'm up a while, it seems fine. I mean I've been a little light-headed lately. But these two big episodes are only in the morning. If it was a brain met, wouldn't it give me trouble other times of the day too? I suppose I should call or email my doctor but wanted to run it by you all first. I am diabetic, but my glucose is pretty good and doesn't fluctuate much. After my dad's quadruple by-pass last month, we've all been on a pretty healthy diet.

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d.wood's picture
Replies 7
Last reply 8/1/2010 - 9:41pm

My husband is stage 3 survivor. We celebrated our 40th wedding anniversary by going hiking in the Grand Canyon. Sun protective clothing, SPF 70 sunscreen, hats and sunglasses....3 days and NO sunburns or tans. We had a ball! We never thought we could do such a thing. It is possible. :) There's life after melanoma! Yea!

Psalm 15

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 Tim... in a msg you posted the other day you said the 'tiny window' would be gone with the upgrade.... 

Does that need to be selected someplace?



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Nancy's picture
Replies 6
Last reply 7/30/2010 - 11:44pm
Replies by: jag, Nancy, NicOz, Tim--MRF

You could see everything on the old board - who responded and what responce was given by whom by scrolling...

read what you needed or may need later,  helpful info - easy to use..

It may be that I'm too old to learn new tricks, but the old way was much better than this new board...

Is there any - like voting for what the majority wants - regarding the board, or not??

Hopefully, we'll get back to the 'old way' soon..





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washoegal's picture
Replies 3
Last reply 7/30/2010 - 8:16am
Replies by: kwahlbin, washoegal

what is the order in whish the posts are displayed?  Doesn't make much snese to me.  Also, any way we could see more per page. Like dropping the banner and jst have a back to home button.

Life is too short to be anything but happy. Falling down is a part of life, getting back up is living.

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   I think you are asking me why I didnt do systemic treatment....I was given that option along with the option of going to Boston for the ILP......and I went down for the consult at Mass General and felt the ILP was a good option for me....and I would "save" the bio chemo for "later" the ILO has an 85% "cure" rate.....according to the surgeon I saw who did the procedure...I was NED for 7 months after the anyways after two more reoccurences (now have had 6), the only treatment offered (other than clinical trials, which werent offered but I looked into and decided I ddint want to do any yet), was I thought I would do that again.....shut down the lymph channels as I have in transit (in the lymph system) mets.....does this help????

Donna in Vermont (now Vermont_Donna) 3 

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Hi guys.

A huge thanks for the following advancement.

Activity is based upon the time of the last reply and not on the time of the original posting. This way an active discussion stays near the top of the board.

I used to find it annoying on the old board when I had to go back 3 or 4 pages sometimes to read new replies to an older active posting of interest to me.

I put that badly. All postings are important to me as they represent feelings of fellow patients but some postings capture my attention a teency more.

Good job guys

miket or talian44

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jim Breitfeller's picture
Replies 3
Last reply 7/2/2011 - 4:24am

One of many immunotolerance mechanisms that immune system has developed to distinguish between self and non-self antigens is regulatory T cells or Tregs.

These cells are recently characterized specialized T-cell subsets that actively suppress a variety of immune responses. Researchers have broadly classified Tregs into natural and adaptive Tregs. Natural Tregs are CD4+CD25+ T-cells that originate in the thymus and play a significant role in immune homeostasis and protection against autoimmunity. Adaptive Tregs are non-regulatory CD4+ T-cells that have up-regulated CD25 expression during pathological and inflammatory conditions such as cancers and infections.

Although the principal immunosuppressive mechanism of Tregs remains elusive, several in vivo experimental models have indicated that Tregs secrete large amounts of immunosuppressants including IL-9, IL-10 and TGF-Beta; upon activation.


These lymphokines are capable of inhibiting activation of Th1, Th2 cells and CTLs required for cell-mediated immunity, inflammation and antibody production. Certain recent experimental data and results even indicate that IL-2-IL-2R signaling is vital for development, maintenance, survival, expansion and suppressive activity of Tregs. Increased expression of certain other characteristic markers including CTLA-4, glucocorticoid-inducible tumor necrosis factor receptor (GITR) and OX40 has been identified on Tregs whose function inside these cells is still not clear. The TCRs displayed on Tregs are capable of recognizing and interacting with any peptide-MHC class II ligand having certain range of avidity. But, the contribution of TCR signaling and role of TCR-ligand interactions towards regulatory T-cell development needs to be determined.


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Gowri Sivaraman's picture
Replies 3
Last reply 8/3/2010 - 1:55am
Replies by: JerryfromFauq, Carver, akls

My father's pet scan results came out clean and the oncologist asked us to follow up with blood tests after 4 months. He has been on interfereon after his lymph node removal last year. This forum has helped in educating me what are the different options available. We think about everyday as a gift these days and i am happy for this moment even though i don't know what the future holds for my father.



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rlaraia's picture
Replies 4
Last reply 4/25/2012 - 11:24pm

I received Michelle's pathology report and the lesion that was removed last week was benign.  The report states it was a Junctional Melanocytic Nevus with nests of typical melanocytes.


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Jan in OC's picture
Replies 4
Last reply 8/6/2010 - 10:10pm
Replies by: Andyb, lilred75, Jan in OC, JenC

 We are planning to move soon and are considering Oregon.  Anyone from there that has a Melonoma oncologist?  Where do you get treatment if you live in Oregon? Husband (Dirk) is currently Stage IV in BRAF clinical trial at UCLA.

laughter is the best medicine

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Nancy's picture
Replies 2
Last reply 7/29/2010 - 8:10pm
Replies by: kwahlbin, sal d

I can't figure this one out- sorry -

You would think they would make it easier --




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Charlie S's picture
Replies 1
Last reply 7/29/2010 - 4:12pm
Replies by: kwahlbin

ONLY on registration are we asked for a birthdate, birthdate is not listed or asked for anywhere else, so why is my birthday (even though it is a fake birthdate) showing up in the right hand field when clicking on my profile?

I posted it here because many people do have privacy concerns, and this would certainly be a privacy concern.


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Anonymous's picture
Replies 3
Last reply 7/29/2010 - 4:02pm
Replies by: kwahlbin, Anonymous

Just wanting to see if the bold, italics, and underline features function and if inserting a link shows and functions as a link directly in the body of the text. 

If all this works I'll give it a   and if not a  .  I see if you enter an emoticon and press the space bar it insert the emoticon, then left click your mouse  THEN press the space bar and presto.... yep, that works

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Anonymous's picture
Replies 2
Last reply 7/29/2010 - 4:44pm
Replies by: gbaum, kwahlbin

 Help finding old posts in archives?

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